A Microfluidic Cartridge System for Multiplexed Clinical Analysis

Walson Lawi; Chris Wiita; Steven T. Snyder; Fang Wei; David Wong; Pak Kin Wong; Joseph C. Liao; David Haake; Vincent Gau

doi:10.1016/j.jala.2009.05.002

A Microfluidic Cartridge System for Multiplexed Clinical Analysis

Walson Lawi, Chris Wiita, Steven T. Snyder, Fang Wei, David Wong, Pak Kin Wong, Joseph C. Liao, David Haake, Vincent Gau

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Cartridge-based microfluidics is a promising technology for clinical diagnostics. By miniaturizing the fluid-handling processes required for genomic and proteomic analyses, reagent and specimen volume is minimized along with the size of the system. We demonstrate an automated microfluidic system capable of performing six multiplexed genomic and proteomic analyses simultaneously, by means of an integrated electrochemical sensor and embedded controls.

Original language	English (US)
Pages (from-to)	407-412
Number of pages	6
Journal	JALA - Journal of the Association for Laboratory Automation
Volume	14
Issue number	6
DOIs	https://doi.org/10.1016/j.jala.2009.05.002
State	Published - Dec 2009

All Science Journal Classification (ASJC) codes

Computer Science Applications
Medical Laboratory Technology

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10.1016/j.jala.2009.05.002

Cite this

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title = "A Microfluidic Cartridge System for Multiplexed Clinical Analysis",

abstract = "Cartridge-based microfluidics is a promising technology for clinical diagnostics. By miniaturizing the fluid-handling processes required for genomic and proteomic analyses, reagent and specimen volume is minimized along with the size of the system. We demonstrate an automated microfluidic system capable of performing six multiplexed genomic and proteomic analyses simultaneously, by means of an integrated electrochemical sensor and embedded controls.",

author = "Walson Lawi and Chris Wiita and Snyder, {Steven T.} and Fang Wei and David Wong and Wong, {Pak Kin} and Liao, {Joseph C.} and David Haake and Vincent Gau",

note = "Funding Information: The development presented in this study was partially supported by Bioengineering Research Partnership R01 EB00127 from the National Institute of Biomedical Imaging and Bioengineering, U01 AI075565–01, U01 AI082457–01 from National Institute of Allergy and Infectious Diseases, U01 DE17790 from the National Institute of Dental and Craniofacial Research, and Department of Veterans Affairs Merit Review B4872R.",

year = "2009",

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doi = "10.1016/j.jala.2009.05.002",

language = "English (US)",

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T1 - A Microfluidic Cartridge System for Multiplexed Clinical Analysis

AU - Lawi, Walson

AU - Wiita, Chris

AU - Snyder, Steven T.

AU - Wei, Fang

AU - Wong, David

AU - Wong, Pak Kin

AU - Liao, Joseph C.

AU - Haake, David

AU - Gau, Vincent

N1 - Funding Information: The development presented in this study was partially supported by Bioengineering Research Partnership R01 EB00127 from the National Institute of Biomedical Imaging and Bioengineering, U01 AI075565–01, U01 AI082457–01 from National Institute of Allergy and Infectious Diseases, U01 DE17790 from the National Institute of Dental and Craniofacial Research, and Department of Veterans Affairs Merit Review B4872R.

PY - 2009/12

Y1 - 2009/12

N2 - Cartridge-based microfluidics is a promising technology for clinical diagnostics. By miniaturizing the fluid-handling processes required for genomic and proteomic analyses, reagent and specimen volume is minimized along with the size of the system. We demonstrate an automated microfluidic system capable of performing six multiplexed genomic and proteomic analyses simultaneously, by means of an integrated electrochemical sensor and embedded controls.

AB - Cartridge-based microfluidics is a promising technology for clinical diagnostics. By miniaturizing the fluid-handling processes required for genomic and proteomic analyses, reagent and specimen volume is minimized along with the size of the system. We demonstrate an automated microfluidic system capable of performing six multiplexed genomic and proteomic analyses simultaneously, by means of an integrated electrochemical sensor and embedded controls.

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DO - 10.1016/j.jala.2009.05.002

M3 - Review article

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A Microfluidic Cartridge System for Multiplexed Clinical Analysis

Abstract

All Science Journal Classification (ASJC) codes

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