Abstract
(Matrix presented) A mild new synthetic procedure has been developed for in situ generation and cyclization of iminyl radicals onto pendant alkenes, followed by functionalization of the resulting carbon radical by one of a variety of trapping reagents. The key process in the method involves production of the iminyl radical via treatment of an aldoxime or ketoxime with readily available 2,6-dimethylbenzenesulfinyl chloride at -50°C to room temperature (Hudson reaction).
Original language | English (US) |
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Pages (from-to) | 637-639 |
Number of pages | 3 |
Journal | Organic Letters |
Volume | 1 |
Issue number | 4 |
DOIs | |
State | Published - Aug 26 1999 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry