A new synthesis of double labeled [7, 9 ‐13C2] folic acid

Marlon Cowart, Christopher J. Falzone, Stephen J. Benkovic

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4 Scopus citations


A convenient small scale chemical synthesis of double labeled folic acid with 13C at positions C‐7 and C‐9 is reported. [1,3‐13C2] acetone was converted into folic acid in two steps, with [1, 1, 3]‐trichloroacetone as the labeled intermediate.

Original languageEnglish (US)
Pages (from-to)67-71
Number of pages5
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number1
StatePublished - Jan 1994

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry


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