A New Total Synthesis of the Fungal Toxin Slaframine

Richard A. Gobao, Martin L. Bremmer, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


Slaframine (1) has been synthesized from diene aldehyde 2. An intramolecular imino Diels-Alder reaction has been used to produce the indolizidine skeleton and to establish the requisite stereochemistry of this fungal metabolite.

Original languageEnglish (US)
Pages (from-to)7065-7068
Number of pages4
JournalJournal of the American Chemical Society
Issue number25
StatePublished - 1982

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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