A new total synthesis of the marine tunicate alkaloid lepadiformine

Pu Sun, Cuixiang Sun, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


(matrix presented) A total synthesis of racemic lepadiformine has been achieved via a route that utilizes as key steps a novel stereocontrolled intramolecular spirocyclization of an allylsilane/N-acyliminium ion and the application of our radical-based methodology for production of N-acylimines from o-aminobenzamides.

Original languageEnglish (US)
Pages (from-to)3507-3510
Number of pages4
JournalOrganic Letters
Issue number22
StatePublished - Nov 1 2001

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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