Abstract
Carbon nucleophiles are alkylated with π-allylpalladium complexes formed by the palladium-catalyzed Heck reaction of a vinyl bromide and an olefin. This methodology achieves the consecutive formation of two carbon-carbon bonds in one simple operation and can be applied both inter- and intramolecularly. The rapid construction of functionalized carbobicyclic compounds is effected by the intramolecular version of this condensation.
Original language | English (US) |
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Pages (from-to) | 9301-9318 |
Number of pages | 18 |
Journal | Tetrahedron |
Volume | 51 |
Issue number | 34 |
DOIs | |
State | Published - Aug 21 1995 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry