TY - JOUR
T1 - A panel study of airborne particulate matter concentration and impaired cardiopulmonary function in young adults by two different exposure measurement
AU - Hu, Li Wen
AU - Qian, Zhengmin (Min)
AU - Bloom, Michael S.
AU - Nelson, Erik J.
AU - Liu, Echu
AU - Han, Bin
AU - Zhang, Nan
AU - Liu, Yimin
AU - Ma, Huimin
AU - Chen, Duo Hong
AU - Yang, Bo Yi
AU - Zeng, Xiao Wen
AU - Chen, Wen
AU - Komppula, Mika
AU - Leskinen, Ari
AU - Hirvonen, Maija Riitta
AU - Roponen, Marjut
AU - Jalava, Pasi
AU - Bai, Zhipeng
AU - Dong, Guang Hui
N1 - Publisher Copyright:
© 2018 Elsevier Ltd
PY - 2018/5
Y1 - 2018/5
N2 - This study sought to clarify the correlation of individual exposure measurements and PM2.5 measurements collected at regulatory monitoring sites in short-term panel study settings. To achieve this goal, 30 young, healthy adult participants were assigned to three groups with 4 samplers in each group to collect individual exposures during four weekends in March 2016. Participants also completed cardiopulmonary function tests during the same periods. For comparison, ambient air pollution data were obtained from the Air Pollution Surveillance Network in Guangzhou, China. The 8-h ambient pollutant averages and group sampler concentrations were used as separate indicators of air pollution exposure. Results showed that the 8-h mean concentration of personal PM2.5 exposure was 65.09 ± 22.18 μg/m3, which was 24.34 μg/m3 statistically higher than the ambient concentrations over the same period (p < 0.05). However, these concentrations were strongly correlated (Spearman's r = 0.937, p < 0.01). Separate mixed-effect models were fit for ambient and personal exposures to estimate their associations with cardiopulmonary outcomes. Higher PM2.5 and PM10 exposures were related to lower lung function of maximal mid-expiratory flow (MMEF). A 10 μg/m3 higher PM was associated with 0.11 L/S to 0.52 L/S lower MMEF. No effects on cardiovascular function were found. In conclusion, personal PM2.5 exposure might be higher than ambient concentrations. Young, healthy adults in urban areas may experience reduced lung function (lower MMEF), even after just 8 h of exposure to PM2.5 and PM10. The comparatives of the effects of ambient pollutant and individual concentrations on human health will help to understand the validity of utilizing ambient monitoring as a surrogate for individual exposure assessment.
AB - This study sought to clarify the correlation of individual exposure measurements and PM2.5 measurements collected at regulatory monitoring sites in short-term panel study settings. To achieve this goal, 30 young, healthy adult participants were assigned to three groups with 4 samplers in each group to collect individual exposures during four weekends in March 2016. Participants also completed cardiopulmonary function tests during the same periods. For comparison, ambient air pollution data were obtained from the Air Pollution Surveillance Network in Guangzhou, China. The 8-h ambient pollutant averages and group sampler concentrations were used as separate indicators of air pollution exposure. Results showed that the 8-h mean concentration of personal PM2.5 exposure was 65.09 ± 22.18 μg/m3, which was 24.34 μg/m3 statistically higher than the ambient concentrations over the same period (p < 0.05). However, these concentrations were strongly correlated (Spearman's r = 0.937, p < 0.01). Separate mixed-effect models were fit for ambient and personal exposures to estimate their associations with cardiopulmonary outcomes. Higher PM2.5 and PM10 exposures were related to lower lung function of maximal mid-expiratory flow (MMEF). A 10 μg/m3 higher PM was associated with 0.11 L/S to 0.52 L/S lower MMEF. No effects on cardiovascular function were found. In conclusion, personal PM2.5 exposure might be higher than ambient concentrations. Young, healthy adults in urban areas may experience reduced lung function (lower MMEF), even after just 8 h of exposure to PM2.5 and PM10. The comparatives of the effects of ambient pollutant and individual concentrations on human health will help to understand the validity of utilizing ambient monitoring as a surrogate for individual exposure assessment.
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U2 - 10.1016/j.atmosenv.2018.03.001
DO - 10.1016/j.atmosenv.2018.03.001
M3 - Article
AN - SCOPUS:85042856067
SN - 1352-2310
VL - 180
SP - 103
EP - 109
JO - Atmospheric Environment
JF - Atmospheric Environment
ER -
