@inproceedings{aeb3787372794449a5765d0475b8e0ab,
title = "A Portable Device Integrated with Aligned Carbon Nanotubes for Sensitive Virus Capture and Detection",
abstract = "Point-of-care virus diagnosis is highly desirable in worldwide infectious disease control. Here we report a hand-held device for capturing viruses by applying physical size based exclusion inside a point-of-care device integrated with vertically aligned carbon nanotube (VACNT) nanostructures to achieve label-free and high throughput virus capture. The microfluidic device is constructed from a VACNT channel wall synthesized bottom-up via chemical vapor deposition (CVD). The VACNT has 117 nm average gap size and 97 porosity. By bonding with a polydimethylsiloxane (PDMS) cover sealing the top, the aqueous sample containing virus particles filter through the VACNT channel wall under negative pressure applied at the outlet end. We have demonstrated that the device is capable of filtering 50 μL of PBS containing 6.3 × 104 counts of lentivirus particles in 10 minutes with 97 of capture efficiency, quantified by the cell infectious titration technique.",
author = "Yeh, {Yin Ting} and Huaguang Lu and Zheng, {Si Yang} and Terrones, {And Mauricio}",
note = "Publisher Copyright: {\textcopyright} 2018 IEEE.; 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 ; Conference date: 18-07-2018 Through 21-07-2018",
year = "2018",
month = oct,
day = "26",
doi = "10.1109/EMBC.2018.8513515",
language = "English (US)",
series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "6072--6075",
booktitle = "40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018",
address = "United States",
}
