A rehabilitation of the genetic map of the 84B-D region in Drosophila melanogaster.

D. R. Cavener, D. C. Otteson, T. C. Kaufman

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


A reanalysis of the 84B3 to 84D3,5 region of the polytene chromosomes of Drosophila melanogaster has led to the identification and localization of 16 genes. These genes include 11 vital loci, four genes exhibiting nonlethal visible mutant phenotypes and one gene encoding a nonessential enzyme. The identity of the gene products of two of the vital genes has been determined to be alpha-tubulin and glucose dehydrogenase (Gld). Three newly identified genes, sticking (stk), half out (hat) and trapped (ted), as well as Gld are required for eclosion. Among the nonessential genes are roughened eye (roe) and ruffed eye (rue), which affect eye texture. The roe phenotype is greatly enhanced by deletions that simultaneously remove roe and an unidentified locus in 84E. Mutations in another nonessential gene, rotund (rn), are characterized by pattern deletions of most adult appendages.

Original languageEnglish (US)
Pages (from-to)111-123
Number of pages13
Issue number1
StatePublished - Sep 1986

All Science Journal Classification (ASJC) codes

  • Genetics


Dive into the research topics of 'A rehabilitation of the genetic map of the 84B-D region in Drosophila melanogaster.'. Together they form a unique fingerprint.

Cite this