A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)

N. Malvadkar; P. Kao; H. Wang; D. L. Allara; M. C. Demirel

A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)

N. Malvadkar, P. Kao, H. Wang, D. L. Allara, M. C. Demirel

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible "fingerprint" of E.Coli on a nanostructured polymer substrate coated with SERS active metals.

Original language	English (US)
Title of host publication	Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Pages	555-557
Number of pages	3
State	Published - Oct 1 2008
Event	2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008 - Quebec City, QC, United States Duration: Jun 1 2008 → Jun 5 2008

Publication series

Name	Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Volume	2

Other

Other	2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008
Country/Territory	United States
City	Quebec City, QC
Period	6/1/08 → 6/5/08

All Science Journal Classification (ASJC) codes

Mechanical Engineering

Cite this

Malvadkar, N., Kao, P., Wang, H., Allara, D. L., & Demirel, M. C. (2008). A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008 (pp. 555-557). (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008; Vol. 2).

Malvadkar, N. ; Kao, P. ; Wang, H. et al. / A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. 2008. pp. 555-557 (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008).

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title = "A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)",

abstract = "Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible {"}fingerprint{"} of E.Coli on a nanostructured polymer substrate coated with SERS active metals.",

author = "N. Malvadkar and P. Kao and H. Wang and Allara, {D. L.} and Demirel, {M. C.}",

year = "2008",

month = oct,

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language = "English (US)",

isbn = "9781420085075",

series = "Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008",

pages = "555--557",

booktitle = "Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008",

note = "2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008 ; Conference date: 01-06-2008 Through 05-06-2008",

}

Malvadkar, N, Kao, P, Wang, H, Allara, DL & Demirel, MC 2008, A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). in Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008, vol. 2, pp. 555-557, 2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008, Quebec City, QC, United States, 6/1/08.

A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). / Malvadkar, N.; Kao, P.; Wang, H. et al.
Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. 2008. p. 555-557 (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)

AU - Malvadkar, N.

AU - Kao, P.

AU - Wang, H.

AU - Allara, D. L.

AU - Demirel, M. C.

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Y1 - 2008/10/1

N2 - Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible "fingerprint" of E.Coli on a nanostructured polymer substrate coated with SERS active metals.

AB - Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible "fingerprint" of E.Coli on a nanostructured polymer substrate coated with SERS active metals.

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M3 - Conference contribution

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BT - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008

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Y2 - 1 June 2008 through 5 June 2008

ER -

Malvadkar N, Kao P, Wang H, Allara DL, Demirel MC. A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. 2008. p. 555-557. (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008).

A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)

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