A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis.

Grant R. Krow; James T. Carey; Kevin C. Cannon; Kenneth J. Henz

doi:10.1016/S0040-4039(00)87386-4

A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis.

Grant R. Krow
, James T. Carey
, Kevin C. Cannon
, Kenneth J. Henz

Division of Engineering and Science (Abington)

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Cycloaddition of N-carbethoxy-2-alkyl-1,2-dihydropyridines 4 with phenylvinylsulfone 5 provides adducts 6, which upon desulfonylation afford stereoselectively N-carbethoxy-3-endo- alkyl-5,6-dehydroisoquinuclidines 1.

Original language	English (US)
Pages (from-to)	2527-2528
Number of pages	2
Journal	Tetrahedron Letters
Volume	23
Issue number	25
DOIs	https://doi.org/10.1016/S0040-4039(00)87386-4
State	Published - 1982

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)87386-4

Cite this

@article{6f826638daea48b69073ea2e4d603d6c,

title = "A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis.",

abstract = "Cycloaddition of N-carbethoxy-2-alkyl-1,2-dihydropyridines 4 with phenylvinylsulfone 5 provides adducts 6, which upon desulfonylation afford stereoselectively N-carbethoxy-3-endo- alkyl-5,6-dehydroisoquinuclidines 1.",

author = "Krow, \{Grant R.\} and Carey, \{James T.\} and Cannon, \{Kevin C.\} and Henz, \{Kenneth J.\}",

year = "1982",

doi = "10.1016/S0040-4039(00)87386-4",

language = "English (US)",

volume = "23",

pages = "2527--2528",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "25",

}

TY - JOUR

T1 - A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis.

AU - Krow, Grant R.

AU - Carey, James T.

AU - Cannon, Kevin C.

AU - Henz, Kenneth J.

PY - 1982

Y1 - 1982

N2 - Cycloaddition of N-carbethoxy-2-alkyl-1,2-dihydropyridines 4 with phenylvinylsulfone 5 provides adducts 6, which upon desulfonylation afford stereoselectively N-carbethoxy-3-endo- alkyl-5,6-dehydroisoquinuclidines 1.

AB - Cycloaddition of N-carbethoxy-2-alkyl-1,2-dihydropyridines 4 with phenylvinylsulfone 5 provides adducts 6, which upon desulfonylation afford stereoselectively N-carbethoxy-3-endo- alkyl-5,6-dehydroisoquinuclidines 1.

UR - https://www.scopus.com/pages/publications/0003623863

UR - https://www.scopus.com/pages/publications/0003623863#tab=citedBy

U2 - 10.1016/S0040-4039(00)87386-4

DO - 10.1016/S0040-4039(00)87386-4

M3 - Article

AN - SCOPUS:0003623863

SN - 0040-4039

VL - 23

SP - 2527

EP - 2528

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 25

ER -

A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis.

Abstract

All Science Journal Classification (ASJC) codes

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