Previous studies have identified viable flyby trajectories to several large trans-Neptunian Objects. In the present study, the potential for orbital capture is examined at Huya, Ixion, Orcus, Rhadamanthus, Salacia, Sedna, and Varuna. Transit times are limited to 25 years; all trajectories use a gravity assist flyby at Jupiter and assume launch either on an Atlas V 551 or a Delta IV HLV. For selected cases, payloads in excess of 200 kg can be captured into orbit about the target, with Huya and Ixion being the most promising candidates. While the emphasis of this study is on high-thrust trajectories, a single low thrust mission to Huya is considered for comparison, yielding favorable results.