Abstract
Implications • Basic digestive processes result in the breakdown of most foodborne antigens; however, a small proportion of food-derived antigens cross the intestinal barrier leading to a brief period of hypersensitivity that is usually followed by the development of oral tolerance. • A shift from oral tolerance to sensitization marks the potential for clinical allergy development. • The anatomical, physiological, histological, genomic homology, and immunological similarity between pigs and humans make pigs a better model than traditional rodent species to study food allergies and intervention strategies. • A subset of pigs naturally develop soy allergies making them an ideal model for soy allergies.
Original language | English (US) |
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Pages (from-to) | 52-59 |
Number of pages | 8 |
Journal | Animal Frontiers |
Volume | 9 |
Issue number | 3 |
DOIs | |
State | Published - Jun 25 2019 |
All Science Journal Classification (ASJC) codes
- Food Animals
- Animal Science and Zoology