A synaptogenic pacing cell line

Ricardo Silva; Eric Barrett; Jamie Kowal; Ji Sung Kim; Harry Allcock; Roger Gaumond

doi:10.1109/CNE.2005.1419606

A synaptogenic pacing cell line

Ricardo Silva, Eric Barrett, Jamie Kowal, Ji Sung Kim, Harry Allcock, Roger Gaumond

Research output: Contribution to conference › Paper › peer-review

Abstract

The SK-N-BE(2c) is an I-type neuroblastoma that develops a strong pacing electrical response over time. This response is likely the result of a developing interconnected network, such that the regular pacemaker-like firing of individual cells becomes synchronous over time forming a Multi Unit Spikes signal (MUS). Immuno-fluorescence was used to show the presence of pre and postsynaptic markers, suggesting that MUS are the result of networking. Hence this cell line could prove as a useful model for synaptic dopaminergic pacing cell systems.

Original language	English (US)
Pages	260-261
Number of pages	2
DOIs	https://doi.org/10.1109/CNE.2005.1419606
State	Published - Dec 1 2005
Event	2nd International IEEE EMBS Conference on Neural Engineering, 2005 - Arlington, VA, United States Duration: Mar 16 2005 → Mar 19 2005

Other

Other	2nd International IEEE EMBS Conference on Neural Engineering, 2005
Country/Territory	United States
City	Arlington, VA
Period	3/16/05 → 3/19/05

All Science Journal Classification (ASJC) codes

General Engineering

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10.1109/CNE.2005.1419606

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author = "Ricardo Silva and Eric Barrett and Jamie Kowal and Kim, {Ji Sung} and Harry Allcock and Roger Gaumond",

year = "2005",

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doi = "10.1109/CNE.2005.1419606",

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note = "2nd International IEEE EMBS Conference on Neural Engineering, 2005 ; Conference date: 16-03-2005 Through 19-03-2005",

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T1 - A synaptogenic pacing cell line

AU - Silva, Ricardo

AU - Barrett, Eric

AU - Kowal, Jamie

AU - Kim, Ji Sung

AU - Allcock, Harry

AU - Gaumond, Roger

PY - 2005/12/1

Y1 - 2005/12/1

N2 - The SK-N-BE(2c) is an I-type neuroblastoma that develops a strong pacing electrical response over time. This response is likely the result of a developing interconnected network, such that the regular pacemaker-like firing of individual cells becomes synchronous over time forming a Multi Unit Spikes signal (MUS). Immuno-fluorescence was used to show the presence of pre and postsynaptic markers, suggesting that MUS are the result of networking. Hence this cell line could prove as a useful model for synaptic dopaminergic pacing cell systems.

AB - The SK-N-BE(2c) is an I-type neuroblastoma that develops a strong pacing electrical response over time. This response is likely the result of a developing interconnected network, such that the regular pacemaker-like firing of individual cells becomes synchronous over time forming a Multi Unit Spikes signal (MUS). Immuno-fluorescence was used to show the presence of pre and postsynaptic markers, suggesting that MUS are the result of networking. Hence this cell line could prove as a useful model for synaptic dopaminergic pacing cell systems.

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T2 - 2nd International IEEE EMBS Conference on Neural Engineering, 2005

Y2 - 16 March 2005 through 19 March 2005

ER -

A synaptogenic pacing cell line

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