@article{8e12c2ac1ce248bd84ec80caea7aa259,
title = "A unified photoredox-catalysis strategy for C(sp3)-H hydroxylation and amidation using hypervalent iodine",
abstract = "We report a unified photoredox-catalysis strategy for both hydroxylation and amidation of tertiary and benzylic C-H bonds. Use of hydroxyl perfluorobenziodoxole (PFBl-OH) oxidant is critical for efficient tertiary C-H functionalization, likely due to the enhanced electrophilicity of the benziodoxole radical. Benzylic methylene C-H bonds can be hydroxylated or amidated using unmodified hydroxyl benziodoxole oxidant Bl-OH under similar conditions. An ionic mechanism involving nucleophilic trapping of a carbocation intermediate by H2O or CH3CN cosolvent is presented.",
author = "Li, {Guo Xing} and Morales-Rivera, {Cristian A.} and Fang Gao and Yaxin Wang and Gang He and Peng Liu and Gong Chen",
note = "Funding Information: We greatly thank the State Key Laboratory of Elemento-Organic Chemistry at Nankai University, and NSFC 21421062, 21672105 for nancial support of this work. DFT calculations were performed using supercomputer resources at the Center for Simulation and Modeling at the University of Pittsburgh, and the Extreme Science and Engineering Discovery Environment supported by the National Science Foundation. Publisher Copyright: {\textcopyright} 2017 The Royal Society of Chemistry.",
year = "2017",
doi = "10.1039/c7sc02773g",
language = "English (US)",
volume = "8",
pages = "7180--7185",
journal = "Chemical Science",
issn = "2041-6520",
publisher = "Royal Society of Chemistry",
number = "10",
}