TY - JOUR
T1 - Acceptance of home and clinic-based cystic fibrosis carrier education and testing by first, second, and third degree relatives of cystic fibrosis patients
AU - Sorenson, J. R.
AU - Cheuvront, B.
AU - DeVellis, B.
AU - Callanan, N.
AU - Silverman, L.
AU - Koch, G.
AU - Sharp, T.
AU - Fernald, G.
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1997/5/16
Y1 - 1997/5/16
N2 - We contacted and offered free cystic fibrosis (CF) carrier education and testing to the first, second, and third degree relatives of individuals with CF followed at a large Southeastern US CF Clinic. Relatives were offered CF carrier education and testing either in their homes or in a genetic counseling clinic. Overall, of 514 relatives offered free CF carrier education and testing, 299 (58%) accepted. Significantly more (67%) of those offered education and testing in their homes accepted than those offered education and testing in a genetic counseling clinic (45%). Regression analyses identified several factors, including education, income, gender, perceived chance of being a carrier, and perceived chance of having a child who is a CF carrier, as predictors of acceptance of education and testing in both home and clinic sites. A smaller set of factors was identified that predicted acceptance of education and testing unique to each site. Within the limits of this study and its design, even when CF carrier testing is offered free of charge, including education and testing in the home, acceptance of education and testing, while higher than in general population samples, is not universal among at-risk relatives. Several factors which may have contributed to the observations reported in this study are discussed.
AB - We contacted and offered free cystic fibrosis (CF) carrier education and testing to the first, second, and third degree relatives of individuals with CF followed at a large Southeastern US CF Clinic. Relatives were offered CF carrier education and testing either in their homes or in a genetic counseling clinic. Overall, of 514 relatives offered free CF carrier education and testing, 299 (58%) accepted. Significantly more (67%) of those offered education and testing in their homes accepted than those offered education and testing in a genetic counseling clinic (45%). Regression analyses identified several factors, including education, income, gender, perceived chance of being a carrier, and perceived chance of having a child who is a CF carrier, as predictors of acceptance of education and testing in both home and clinic sites. A smaller set of factors was identified that predicted acceptance of education and testing unique to each site. Within the limits of this study and its design, even when CF carrier testing is offered free of charge, including education and testing in the home, acceptance of education and testing, while higher than in general population samples, is not universal among at-risk relatives. Several factors which may have contributed to the observations reported in this study are discussed.
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U2 - 10.1002/(SICI)1096-8628(19970516)70:2<121::AID-AJMG4>3.0.CO;2-0
DO - 10.1002/(SICI)1096-8628(19970516)70:2<121::AID-AJMG4>3.0.CO;2-0
M3 - Article
C2 - 9128929
AN - SCOPUS:0030998549
SN - 0148-7299
VL - 70
SP - 121
EP - 129
JO - American Journal of Medical Genetics
JF - American Journal of Medical Genetics
IS - 2
ER -