Acid catalyzed chlorination of pyrrole with N‐chloroacetanilide

Michael de Rosa

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The chlorination of pyrrole with N‐chloroacetanilide was catalyzed by acetic acid. Transfer of Cl+ occurred directly to the α and β positions of pyrrole and a mixture of 2‐chloro‐, 3‐chloro‐ and 2,5,‐dichloropyrrole was formed. The α↗β ratio was 10:1 under competitive conditions.

Original languageEnglish (US)
Pages (from-to)1585
Number of pages1
JournalJournal of Heterocyclic Chemistry
Volume19
Issue number6
DOIs
StatePublished - 1982

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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