Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures

Adem Ozcelik; Nitesh Nama; Po Hsun Huang; Murat Kaynak; Melanie R. McReynolds; Wendy Hanna-Rose; Tony Jun Huang

doi:10.1002/smll.201601760

Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures

Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang

Research output: Contribution to journal › Article › peer-review

104 Scopus citations

Abstract

A polydimethylsiloxane microchannel featuring sidewall sharp-edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp-edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in-plane and out-of-plane.

Original language	English (US)
Pages (from-to)	5120-5125
Number of pages	6
Journal	Small (Weinheim an der Bergstrasse, Germany)
Volume	12
Issue number	37
DOIs	https://doi.org/10.1002/smll.201601760
State	Published - Oct 1 2016

All Science Journal Classification (ASJC) codes

Biotechnology
Biomaterials
General Chemistry
General Materials Science

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10.1002/smll.201601760

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abstract = "A polydimethylsiloxane microchannel featuring sidewall sharp-edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp-edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in-plane and out-of-plane.",

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AU - Ozcelik, Adem

AU - Nama, Nitesh

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AU - Kaynak, Murat

AU - McReynolds, Melanie R.

AU - Hanna-Rose, Wendy

AU - Huang, Tony Jun

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AB - A polydimethylsiloxane microchannel featuring sidewall sharp-edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp-edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in-plane and out-of-plane.

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Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures

Abstract

All Science Journal Classification (ASJC) codes

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