Acute Renal Failure following Immunoglobulin Therapy

Nasimul Ahsan, Laurel A. Wiegand, Catherine Abendroth, Eric C. Manning

Research output: Contribution to journalArticlepeer-review

61 Scopus citations


Intravenous IgG infusion has infrequently been reported to cause acute renal failure. In almost all these reports, a sucrose containing IgG product was believed to be the cause of renal injury. Sucrose-induced osmotic nephrosis has been well described in the literature. In this report, we describe a case of acute anuric renal failure following a large infusion of intravenous IgG containing sucrose. Urine cytology demonstrated typical osmotic injury to the renal tubular epithelial cells. Early recovery of renal function was achieved by dialytic removal of sucrose from the circulation.

Original languageEnglish (US)
Pages (from-to)532-536
Number of pages5
JournalAmerican Journal of Nephrology
Issue number6
StatePublished - Jan 1 1996

All Science Journal Classification (ASJC) codes

  • Nephrology


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