Adaption by Rewiring Epigenetic Landscapes

Yifei Liu; Andrew Xiao

doi:10.1016/j.stem.2015.08.015

Adaption by Rewiring Epigenetic Landscapes

Yifei Liu
, Andrew Xiao

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Embryonic stem cells (ESCs) generally rely on repressive histone modifications to silence retrotransposons, rather than DNA methylation as in differentiated cells. In this issue of Cell Stem Cell, He et al. (2015) show that Daxx/Atrx repress transposons in ESCs devoid of 5mC, demonstrating dynamic reorganization of epigenetic networks and crosstalk between distinct repressive mechanisms to maintain transposon silencing.

Original language	English (US)
Article number	1841
Pages (from-to)	249-250
Number of pages	2
Journal	Cell Stem Cell
Volume	17
Issue number	3
DOIs	https://doi.org/10.1016/j.stem.2015.08.015
State	Published - Sep 3 2015

All Science Journal Classification (ASJC) codes

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2015.08.015

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title = "Adaption by Rewiring Epigenetic Landscapes",

abstract = "Embryonic stem cells (ESCs) generally rely on repressive histone modifications to silence retrotransposons, rather than DNA methylation as in differentiated cells. In this issue of Cell Stem Cell, He et al. (2015) show that Daxx/Atrx repress transposons in ESCs devoid of 5mC, demonstrating dynamic reorganization of epigenetic networks and crosstalk between distinct repressive mechanisms to maintain transposon silencing.",

author = "Yifei Liu and Andrew Xiao",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = sep,

day = "3",

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T1 - Adaption by Rewiring Epigenetic Landscapes

AU - Liu, Yifei

AU - Xiao, Andrew

PY - 2015/9/3

Y1 - 2015/9/3

N2 - Embryonic stem cells (ESCs) generally rely on repressive histone modifications to silence retrotransposons, rather than DNA methylation as in differentiated cells. In this issue of Cell Stem Cell, He et al. (2015) show that Daxx/Atrx repress transposons in ESCs devoid of 5mC, demonstrating dynamic reorganization of epigenetic networks and crosstalk between distinct repressive mechanisms to maintain transposon silencing.

AB - Embryonic stem cells (ESCs) generally rely on repressive histone modifications to silence retrotransposons, rather than DNA methylation as in differentiated cells. In this issue of Cell Stem Cell, He et al. (2015) show that Daxx/Atrx repress transposons in ESCs devoid of 5mC, demonstrating dynamic reorganization of epigenetic networks and crosstalk between distinct repressive mechanisms to maintain transposon silencing.

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UR - https://www.scopus.com/pages/publications/84940997314#tab=citedBy

U2 - 10.1016/j.stem.2015.08.015

DO - 10.1016/j.stem.2015.08.015

M3 - Short survey

C2 - 26340521

AN - SCOPUS:84940997314

SN - 1934-5909

VL - 17

SP - 249

EP - 250

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 3

M1 - 1841

ER -

Adaption by Rewiring Epigenetic Landscapes

Abstract

All Science Journal Classification (ASJC) codes

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