Adaptive metamorphs model for 3D medical image segmentation

Junzhou Huang, Xiaolei Huang, Dimitris Metaxas, Leon Axel

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations


In this paper, we introduce an adaptive model-based segmentation framework, in which edge and region information are integrated and used adaptively while a solid model deforms toward the object boundary. Our 3D segmentation method stems from Metamorphs deformable models [1]. The main novelty of our work is in that, instead of performing segmentation in an entire 3D volume, we propose model-based segmentation in an adaptively changing subvolume of interest. The subvolume is determined based on appearance statistics of the evolving object model, and within the subvolume, more accurate and object-specific edge and region information can be obtained. This local and adaptive scheme for computing edges and object region information makes our segmentation solution more efficient and more robust to image noise, artifacts and intensity inhomogeneity. External forces for model deformation are derived in a variational framework that consists of both edge-based and region-based energy terms, taking into account the adaptively changing environment. We demonstrate the performance of our method through extensive experiments using cardiac MR and liver CT images.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - 10th International Conference, Proceedings
PublisherSpringer Verlag
Number of pages9
EditionPART 1
ISBN (Print)9783540757566
StatePublished - 2007
Event10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007 - Brisbane, Australia
Duration: Oct 29 2007Nov 2 2007

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 1
Volume4791 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007

All Science Journal Classification (ASJC) codes

  • Theoretical Computer Science
  • General Computer Science


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