Advancing equitable health and well-being across urban–rural sustainable infrastructure systems

Infrastructure systems have direct implications for how health and well-being evolve across urban–rural systems. Scientists, practitioners, and policy-makers use domain-specific methods and tools to characterize sectors of infrastructure, but these approaches do not capture the cascading effects across interrelated infrastructure and governance domains. We argue that the development and management of sustainable urban infrastructure must focus on interactions across urban and rural places to advance equitable health and well-being. We call for a research agenda that focuses on urban–rural infrastructure systems, addressing trade-offs and synergies, decision-making, institutional arrangements, and effective co-production of knowledge across the diverse places connected by infrastructure.