TY - JOUR
T1 - Adverse Effects of Amiodarone
T2 - Pathogenesis, Incidence and Management
AU - Naccarelli, Gerald
AU - Rinkenberger, Robert L.
AU - Dougherty, Anne H.
AU - Fitzgerald, David M.
PY - 1989/8
Y1 - 1989/8
N2 - Amiodarone is an extremely effective antiarrhythmic agent for the treatment of both life-threatening ventricular arrhythmias and refractory supraventricular tachyarrhythmias. Subjective minor side effects are common with amiodarone but rarely require discontinuation of therapy and are often handled by dose reduction. Serious end-organ toxicity, including pulmonry fibrosis and drug-induced hepatitis, have been the most common indications for discontinuing amiodarone therapy in these patients.
AB - Amiodarone is an extremely effective antiarrhythmic agent for the treatment of both life-threatening ventricular arrhythmias and refractory supraventricular tachyarrhythmias. Subjective minor side effects are common with amiodarone but rarely require discontinuation of therapy and are often handled by dose reduction. Serious end-organ toxicity, including pulmonry fibrosis and drug-induced hepatitis, have been the most common indications for discontinuing amiodarone therapy in these patients.
UR - https://www.scopus.com/pages/publications/0024349440
UR - https://www.scopus.com/pages/publications/0024349440#tab=citedBy
U2 - 10.1007/BF03259911
DO - 10.1007/BF03259911
M3 - Review article
C2 - 2671595
AN - SCOPUS:0024349440
SN - 0113-5244
VL - 4
SP - 246
EP - 253
JO - Medical Toxicology and Adverse Drug Experience
JF - Medical Toxicology and Adverse Drug Experience
IS - 4
ER -