TY - JOUR
T1 - Age-related differences in the neural correlates mediating false recollection
AU - Dennis, Nancy A.
AU - Bowman, Caitlin R.
AU - Peterson, Kristina M.
N1 - Funding Information:
This research was supported by a National Science Foundation grant BCS1025709 awarded to NAD and was conducted while NAD was an AFAR Research Grant recipient from the American Federation for Aging Research. The authors thank Avery Rizio, Christina Johnson, and Courtney Allen for helpful comments and Simon Vandekar for assistance with analysis and data collection. Appendix A
PY - 2014/2
Y1 - 2014/2
N2 - The current study investigated the effects of aging on the neural basis underlying true and false recollection. Although older adults, compared with younger adults, exhibited equivalent rates of true recollection, age differences in true recollection showed a pattern of activity commonly found among previous memory studies (e.g., age-related decreases in occipital and increases in prefrontal cortices), suggesting reduced retrieval of perceptual details associated with encoding items and a greater reliance on top-down compensatory processing. With regard to false recollection, older adults exhibited significantly greater false recollection yet did not exhibit increased neural processing. They did exhibit decreased activity in prefrontal, parahippocampal gyrus, and occipitoparietal cortex, suggesting a reduced reliance on reconstruction processes mediating false recollection in young. An individual differences analysis in older adults found false recollection rates predicted activity in several regions. including bilateral middle/superior temporal gyrus. Taken together, these results indicate that increases in false recollection in aging may be mediated by reduced access to encoding-related details as well as reliance on semantic gist and familiarity-related neural activity.
AB - The current study investigated the effects of aging on the neural basis underlying true and false recollection. Although older adults, compared with younger adults, exhibited equivalent rates of true recollection, age differences in true recollection showed a pattern of activity commonly found among previous memory studies (e.g., age-related decreases in occipital and increases in prefrontal cortices), suggesting reduced retrieval of perceptual details associated with encoding items and a greater reliance on top-down compensatory processing. With regard to false recollection, older adults exhibited significantly greater false recollection yet did not exhibit increased neural processing. They did exhibit decreased activity in prefrontal, parahippocampal gyrus, and occipitoparietal cortex, suggesting a reduced reliance on reconstruction processes mediating false recollection in young. An individual differences analysis in older adults found false recollection rates predicted activity in several regions. including bilateral middle/superior temporal gyrus. Taken together, these results indicate that increases in false recollection in aging may be mediated by reduced access to encoding-related details as well as reliance on semantic gist and familiarity-related neural activity.
UR - http://www.scopus.com/inward/record.url?scp=84887232656&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887232656&partnerID=8YFLogxK
U2 - 10.1016/j.neurobiolaging.2013.08.019
DO - 10.1016/j.neurobiolaging.2013.08.019
M3 - Article
C2 - 24094578
AN - SCOPUS:84887232656
SN - 0197-4580
VL - 35
SP - 395
EP - 407
JO - Neurobiology of Aging
JF - Neurobiology of Aging
IS - 2
ER -