TY - JOUR
T1 - Allergic patch test reactions associated with cosmetics
T2 - Retrospective analysis of cross-sectional data from the North American Contact Dermatitis Group, 2001-2004
AU - Warshaw, Erin M.
AU - Buchholz, Heather J.
AU - Belsito, Donald V.
AU - Maibach, Howard I.
AU - Fowler, Joseph F.
AU - Rietschel, Robert L.
AU - Zug, Kathryn A.
AU - Mathias, C. G.Toby
AU - Pratt, Melanie D.
AU - Sasseville, Denis
AU - Storrs, Frances J.
AU - Taylor, James S.
AU - DeLeo, Vincent A.
AU - Marks, James G.
N1 - Funding Information:
Supported by a Women's Dermatologic Society Academic Research Grant Program.
PY - 2009/1
Y1 - 2009/1
N2 - Background: Allergy to cosmetics is common. Objectives: We sought to characterize patients with positive patch test reactions associated with a cosmetic source, to identify common allergens; and to explore gender and occupational associations. Methods: We performed a retrospective, cross-sectional analysis. Results: Of 6621 female and 3440 male patients, 1582 female (23.8%) and 611 of male (17.8%) patients had at least one allergic patch test reaction associated with a cosmetic source. Of "allergic" patients (>1 allergic reaction, n = 6815), females were 1.21 times more likely to have an allergic reaction associated with a cosmetic source than were male patients (p < .0001, 95% confidence interval [CI] 1.12-1.31). Within the "cosmetic allergic" group (n = 2243), head and neck involvement was significantly higher in female than in male patients (49.3% vs 23.7%, p < .0001). One hundred twenty-five patients had occupationally related allergic reactions associated with a cosmetic. Limitations: This study is limited by its cross-sectional, retrospective design. Conclusion: Of all patients studied, 21.8% had an allergic reaction associated with a cosmetic. Site of dermatitis, cosmetic categories, and specific allergens differed somewhat by gender.
AB - Background: Allergy to cosmetics is common. Objectives: We sought to characterize patients with positive patch test reactions associated with a cosmetic source, to identify common allergens; and to explore gender and occupational associations. Methods: We performed a retrospective, cross-sectional analysis. Results: Of 6621 female and 3440 male patients, 1582 female (23.8%) and 611 of male (17.8%) patients had at least one allergic patch test reaction associated with a cosmetic source. Of "allergic" patients (>1 allergic reaction, n = 6815), females were 1.21 times more likely to have an allergic reaction associated with a cosmetic source than were male patients (p < .0001, 95% confidence interval [CI] 1.12-1.31). Within the "cosmetic allergic" group (n = 2243), head and neck involvement was significantly higher in female than in male patients (49.3% vs 23.7%, p < .0001). One hundred twenty-five patients had occupationally related allergic reactions associated with a cosmetic. Limitations: This study is limited by its cross-sectional, retrospective design. Conclusion: Of all patients studied, 21.8% had an allergic reaction associated with a cosmetic. Site of dermatitis, cosmetic categories, and specific allergens differed somewhat by gender.
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U2 - 10.1016/j.jaad.2008.07.056
DO - 10.1016/j.jaad.2008.07.056
M3 - Article
C2 - 18992965
AN - SCOPUS:57649221939
SN - 0190-9622
VL - 60
SP - 23
EP - 38
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 1
ER -