Allosteric and dynamic control of RNA-dependent RNA polymerase function and fidelity

Keyphrases

• Dynamic Control 100%
• RNA-dependent RNA Polymerase (RdRP) 100%
• Nucleotide Selection 40%
• Nucleotide Synthesis 40%
• X-ray Crystallography 20%
• Functional Role 20%
• Thermodynamics 20%
• Molecular Dynamics Simulation 20%
• Moving Parts 20%
• Low Energy Conformations 20%
• Amino Acid Substitution 20%
• Structural Motif 20%
• Antiviral Strategy 20%
• Nuclear Magnetic Resonance 20%
• Active Loop 20%
• RNA Virus 20%
• Coordinated Motion 20%
• Genome Replication 20%
• Dynamic Motion 20%
• Vaccine Strain 20%
• Biophysical Techniques 20%
• Strain Development 20%
• Dynamic Fluctuations 20%
• Conformational Motions 20%
• Macromolecular Machines 20%
• Inhibitor Binding 20%

Biochemistry, Genetics and Molecular Biology

• Motion 100%
• RNA-dependent RNA Polymerase 100%
• X-Ray Crystallography 20%
• Conformation 20%
• Active Site 20%
• Enzyme 20%
• Amino Acid Substitution 20%
• Structural Motif 20%
• Magnetism 20%