Altered biodistribution of gallium-67 in a patient with aluminum toxicity treated with desferoxamine

S. J. Brown, W. J. Slizofski, S. Dadparvar

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Markedly altered biodistribution of [67Ga]citrate was observed in a 66-yr-old hemodialysis patient imaged at 48 hr postinjection. A review of the patient's hospital records revealed toxic serum levels of aluminum, treated with the chelating agent desferoxamine. Based on what is known about the biologic interactions between gallium, aluminum, transferrin, and desferoxamine, we believe that both toxic serum aluminum levels and desferoxamine therapy may cause altered biodistribution on [67Ga]citrate scintigraphy.

Original languageEnglish (US)
Pages (from-to)115-117
Number of pages3
JournalJournal of Nuclear Medicine
Volume31
Issue number1
StatePublished - 1990

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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