Altered mechanisms of vasodilation in aged human skin

Lacy A. Holowatz; Caitlin S. Thompson-Torgerson; W. Larry Kenney

doi:10.1097/jes.0b013e3180a02f85

Altered mechanisms of vasodilation in aged human skin

Lacy A. Holowatz, Caitlin S. Thompson-Torgerson, W. Larry Kenney

Kinesiology

Research output: Contribution to journal › Review article › peer-review

63 Scopus citations

Abstract

Human skin blood flow increases in response to increased body core and local skin temperature via distinct reflex and local mechanisms requiring functional nitric oxide (NO) for full expression. The mechanisms mediating cutaneous vasodilation are impaired with primary aging, resulting in attenuated vasodilation. This article highlights recent findings of how age-related vascular impairments in NO signaling contribute to attenuated cutaneous vasodilation.

Original language	English (US)
Pages (from-to)	119-125
Number of pages	7
Journal	Exercise and Sport Sciences Reviews
Volume	35
Issue number	3
DOIs	https://doi.org/10.1097/jes.0b013e3180a02f85
State	Published - Jul 2007

All Science Journal Classification (ASJC) codes

Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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10.1097/jes.0b013e3180a02f85

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title = "Altered mechanisms of vasodilation in aged human skin",

abstract = "Human skin blood flow increases in response to increased body core and local skin temperature via distinct reflex and local mechanisms requiring functional nitric oxide (NO) for full expression. The mechanisms mediating cutaneous vasodilation are impaired with primary aging, resulting in attenuated vasodilation. This article highlights recent findings of how age-related vascular impairments in NO signaling contribute to attenuated cutaneous vasodilation.",

author = "Holowatz, {Lacy A.} and Thompson-Torgerson, {Caitlin S.} and Kenney, {W. Larry}",

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AU - Thompson-Torgerson, Caitlin S.

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N2 - Human skin blood flow increases in response to increased body core and local skin temperature via distinct reflex and local mechanisms requiring functional nitric oxide (NO) for full expression. The mechanisms mediating cutaneous vasodilation are impaired with primary aging, resulting in attenuated vasodilation. This article highlights recent findings of how age-related vascular impairments in NO signaling contribute to attenuated cutaneous vasodilation.

AB - Human skin blood flow increases in response to increased body core and local skin temperature via distinct reflex and local mechanisms requiring functional nitric oxide (NO) for full expression. The mechanisms mediating cutaneous vasodilation are impaired with primary aging, resulting in attenuated vasodilation. This article highlights recent findings of how age-related vascular impairments in NO signaling contribute to attenuated cutaneous vasodilation.

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JF - Exercise and Sport Sciences Reviews

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Altered mechanisms of vasodilation in aged human skin

Abstract

All Science Journal Classification (ASJC) codes

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