Altered nutrient response of mTORC1 as a result of changes in REDD1 expression: Effect of obesity vs. REDD1 deficiency

Keyphrases

• Obesity 100%
• Mammalian Target of Rapamycin (mTOR) 100%
• REDD+ 100%
• Nutrient Response 100%
• S6 Kinase 1 (S6K1) 45%
• MTORC1 Signaling 45%
• 4E-BP1 36%
• Knock-in Mouse Model 27%
• Skeletal muscle 27%
• Raptor 27%
• Mouse Skeletal muscle 27%
• Phosphorylation 18%
• Signal Response 18%
• Low Fat 18%
• Fed Condition 18%
• Rheb 18%
• %Fat 9%
• High-fat Diet 9%
• Insulin 9%
• Repressor 9%
• Wild Mice 9%
• Diet-induced 9%
• In the Wild 9%
• Nutrient Intake 9%
• Body Mass 9%
• Diet-induced Obesity 9%
• High-fat Feeding 9%
• Dysregulated 9%

Biochemistry, Genetics and Molecular Biology

• Knockout Mouse 100%
• Skeletal Muscle 100%
• Mammalian Target of Rapamycin 100%
• Wild Type 66%
• Guanosine Triphosphate 66%
• Protein Expression 33%
• Repressor 33%
• Body Mass 33%
• Wild Type Mouse 33%
• Ob/Ob Mouse 33%

Medicine and Dentistry

• Mammalian Target of Rapamycin 100%
• Skeletal Muscle 100%
• Guanosine Triphosphate 66%
• High Fat Food 66%
• Protein Expression 33%
• Nutrient Intake 33%
• Diet Induced Obesity 33%
• Repressor Gene 33%
• Ob/Ob Mouse 33%