Amended Safety Assessment of Parabens as Used in Cosmetics

Priya Cherian, Jinqiu Zhu, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Bart Heldreth

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 21 parabens as preservatives in cosmetic products. All of these ingredients are reported to function in cosmetics as preservatives; however, 5 are reported to also function as fragrance ingredients. The Panel reviewed relevant data relating to the safety of these ingredients under the reported conditions of use in cosmetic formulations. The Panel concluded that 20 of the 21 parabens included in this report are safe in cosmetics in the present practices of use and concentration described in this safety assessment when the sum of the total parabens in any given formulation does not exceed 0.8%. However, the available data are insufficient to support a conclusion of safety for benzylparaben in cosmetics.

Original languageEnglish (US)
Pages (from-to)5S-97S
JournalInternational journal of toxicology
Issue number1_suppl
StatePublished - Jul 1 2020

All Science Journal Classification (ASJC) codes

  • Toxicology


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