Aminoglutethimide-induced hematologic toxicity: Worldwide experience

A. A. Messeih; Allan Lipton; R. J. Santen; Harold Harvey; A. E. Boucher; R. Murray; J. Ragaz; A. U. Buzdar; G. A. Nagel; I. C. Henderson

Aminoglutethimide-induced hematologic toxicity: Worldwide experience

A. A. Messeih
, Allan Lipton
, R. J. Santen
, Harold Harvey
, A. E. Boucher
, R. Murray
, J. Ragaz
, A. U. Buzdar
, G. A. Nagel
, I. C. Henderson

Research output: Contribution to journal › Article › peer-review

Abstract

Marked leukopenia and/or thrombocytopenia occurred in 12 of 1333 patients treated with aminoglutethimide (0.9% incidence). Depression of blood cell counts was evident within 7 weeks of starting treatment. No delayed toxicity was encountered. Blood cell counts recovered promptly upon cessation of aminoglutethimide in all but one patient, who died from septicemia and marrow aplasia.

Original language	English (US)
Pages (from-to)	1003-1004
Number of pages	2
Journal	Cancer Treatment Reports
Volume	69
Issue number	9
State	Published - Dec 11 1985

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

Cite this

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title = "Aminoglutethimide-induced hematologic toxicity: Worldwide experience",

abstract = "Marked leukopenia and/or thrombocytopenia occurred in 12 of 1333 patients treated with aminoglutethimide (0.9\% incidence). Depression of blood cell counts was evident within 7 weeks of starting treatment. No delayed toxicity was encountered. Blood cell counts recovered promptly upon cessation of aminoglutethimide in all but one patient, who died from septicemia and marrow aplasia.",

author = "Messeih, \{A. A.\} and Allan Lipton and Santen, \{R. J.\} and Harold Harvey and Boucher, \{A. E.\} and R. Murray and J. Ragaz and Buzdar, \{A. U.\} and Nagel, \{G. A.\} and Henderson, \{I. C.\}",

year = "1985",

month = dec,

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language = "English (US)",

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pages = "1003--1004",

journal = "Cancer Treatment Reports",

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TY - JOUR

T1 - Aminoglutethimide-induced hematologic toxicity

T2 - Worldwide experience

AU - Messeih, A. A.

AU - Lipton, Allan

AU - Santen, R. J.

AU - Harvey, Harold

AU - Boucher, A. E.

AU - Murray, R.

AU - Ragaz, J.

AU - Buzdar, A. U.

AU - Nagel, G. A.

AU - Henderson, I. C.

PY - 1985/12/11

Y1 - 1985/12/11

N2 - Marked leukopenia and/or thrombocytopenia occurred in 12 of 1333 patients treated with aminoglutethimide (0.9% incidence). Depression of blood cell counts was evident within 7 weeks of starting treatment. No delayed toxicity was encountered. Blood cell counts recovered promptly upon cessation of aminoglutethimide in all but one patient, who died from septicemia and marrow aplasia.

AB - Marked leukopenia and/or thrombocytopenia occurred in 12 of 1333 patients treated with aminoglutethimide (0.9% incidence). Depression of blood cell counts was evident within 7 weeks of starting treatment. No delayed toxicity was encountered. Blood cell counts recovered promptly upon cessation of aminoglutethimide in all but one patient, who died from septicemia and marrow aplasia.

UR - https://www.scopus.com/pages/publications/0022005835

UR - https://www.scopus.com/pages/publications/0022005835#tab=citedBy

M3 - Article

C2 - 4028032

AN - SCOPUS:0022005835

SN - 0361-5960

VL - 69

SP - 1003

EP - 1004

JO - Cancer Treatment Reports

JF - Cancer Treatment Reports

IS - 9

ER -

Aminoglutethimide-induced hematologic toxicity: Worldwide experience

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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