Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma

E. J. Sanford; J. R. Drago; T. J. Rohner; R. Santen; Allan Lipton

doi:10.1016/S0022-5347(17)59121-1

Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma

E. J. Sanford, J. R. Drago, T. J. Rohner, R. Santen, Allan Lipton

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44 Scopus citations

Abstract

Complete adrenal suppression with aminoglutethimide has been accomplished in 7 patients with progressive stage D carcinoma of the prostate who had become refractory to orchiectomy and the administration of exogenous estrogens. A favorable response was noted in 3 patients. These preliminary results indicate that this agent may be as useful as surgical adrenalectomy in the treatment of progressive prostatic carcinoma. A brief discussion of the pharmacology of this agent, its mode of administration and the side effects are presented.

Original language	English (US)
Pages (from-to)	170-174
Number of pages	5
Journal	Unknown Journal
Volume	115
Issue number	2
DOIs	https://doi.org/10.1016/S0022-5347(17)59121-1
State	Published - Jan 1 1976

All Science Journal Classification (ASJC) codes

Urology

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10.1016/S0022-5347(17)59121-1

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AU - Lipton, Allan

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AB - Complete adrenal suppression with aminoglutethimide has been accomplished in 7 patients with progressive stage D carcinoma of the prostate who had become refractory to orchiectomy and the administration of exogenous estrogens. A favorable response was noted in 3 patients. These preliminary results indicate that this agent may be as useful as surgical adrenalectomy in the treatment of progressive prostatic carcinoma. A brief discussion of the pharmacology of this agent, its mode of administration and the side effects are presented.

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Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma

Abstract

All Science Journal Classification (ASJC) codes

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