Abstract
Amiodarone is a benzofuran derivative that has been effective for the treatment of both supraventricular and ventricular tachyarrhythmias. It has a large volume of distribution, moderate bioavailability and a long half‐life. Its pharmacokinetics are not well understood and its tissue distribution is not typical of a 2‐compartment model. Due to ocular, dermatologic, gastrointestinal, neurologic, cardiovascular, thyroid and pulmonary toxicity, amiodarone should be reserved for use in patients with refractory and/or life‐threatening arrhythmias. 1985 Pharmacotherapy Publications Inc.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 298-311 |
| Number of pages | 14 |
| Journal | Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy |
| Volume | 5 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1985 |
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
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