An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America

Todd J. Ward; Randall M. Clear; Alejandro P. Rooney; Kerry O'Donnell; Don Gaba; Susan Patrick; David E. Starkey; Jeannie Gilbert; David M. Geiser; Tom W. Nowicki

doi:10.1016/j.fgb.2007.10.003

An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America

Todd J. Ward, Randall M. Clear, Alejandro P. Rooney, Kerry O'Donnell, Don Gaba, Susan Patrick, David E. Starkey, Jeannie Gilbert, David M. Geiser, Tom W. Nowicki

Research output: Contribution to journal › Article › peer-review

422 Scopus citations

Abstract

Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (F_ST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.

Original language	English (US)
Pages (from-to)	473-484
Number of pages	12
Journal	Fungal Genetics and Biology
Volume	45
Issue number	4
DOIs	https://doi.org/10.1016/j.fgb.2007.10.003
State	Published - Apr 2008

All Science Journal Classification (ASJC) codes

Microbiology
Genetics

Access to Document

10.1016/j.fgb.2007.10.003

Cite this

Ward, T. J., Clear, R. M., Rooney, A. P., O'Donnell, K., Gaba, D., Patrick, S., Starkey, D. E., Gilbert, J., Geiser, D. M., & Nowicki, T. W. (2008). An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America. Fungal Genetics and Biology, 45(4), 473-484. https://doi.org/10.1016/j.fgb.2007.10.003

@article{6911a33210304df0905ffc8078776439,

title = "An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America",

abstract = "Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (FST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.",

author = "Ward, {Todd J.} and Clear, {Randall M.} and Rooney, {Alejandro P.} and Kerry O'Donnell and Don Gaba and Susan Patrick and Starkey, {David E.} and Jeannie Gilbert and Geiser, {David M.} and Nowicki, {Tom W.}",

year = "2008",

month = apr,

doi = "10.1016/j.fgb.2007.10.003",

language = "English (US)",

volume = "45",

pages = "473--484",

journal = "Fungal Genetics and Biology",

issn = "1087-1845",

publisher = "Academic Press Inc.",

number = "4",

}

Ward, TJ, Clear, RM, Rooney, AP, O'Donnell, K, Gaba, D, Patrick, S, Starkey, DE, Gilbert, J, Geiser, DM & Nowicki, TW 2008, 'An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America', Fungal Genetics and Biology, vol. 45, no. 4, pp. 473-484. https://doi.org/10.1016/j.fgb.2007.10.003

TY - JOUR

T1 - An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America

AU - Ward, Todd J.

AU - Clear, Randall M.

AU - Rooney, Alejandro P.

AU - O'Donnell, Kerry

AU - Gaba, Don

AU - Patrick, Susan

AU - Starkey, David E.

AU - Gilbert, Jeannie

AU - Geiser, David M.

AU - Nowicki, Tom W.

PY - 2008/4

Y1 - 2008/4

N2 - Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (FST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.

AB - Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (FST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.

UR - http://www.scopus.com/inward/record.url?scp=39749180997&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=39749180997&partnerID=8YFLogxK

U2 - 10.1016/j.fgb.2007.10.003

DO - 10.1016/j.fgb.2007.10.003

M3 - Article

C2 - 18035565

AN - SCOPUS:39749180997

SN - 1087-1845

VL - 45

SP - 473

EP - 484

JO - Fungal Genetics and Biology

JF - Fungal Genetics and Biology

IS - 4

ER -

An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this