An Electrochemical Design for Catalytic Dehydration: Direct, Room-Temperature Esterification without Acid or Base Additives

Jian Han, Christopher A. Haines, Jacob J. Piane, Leila L. Filien, Eric D. Nacsa

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


An electrochemical approach has been leveraged to underpin a new conceptual platform for dehydration reactions, which has been demonstrated in the context of esterification. Esters were prepared from the corresponding acid and alcohol partners at room temperature without acid or base additives and without consuming stoichiometric reagents. This methodology therefore addresses key complications that plague esterification and dehydration reactions more broadly and that represent a leading challenge in synthetic chemistry.

Original languageEnglish (US)
Pages (from-to)15680-15687
Number of pages8
JournalJournal of the American Chemical Society
Issue number29
StatePublished - Jul 26 2023

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry

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