An exploratory study of depot-medroxyprogesterone acetate and bone mineral density in adolescent and young adult women with cerebral palsy

R. Claire Roden; Garey Noritz; Erin R. McKnight; Andrea E. Bonny

doi:10.1016/j.contraception.2019.12.009

An exploratory study of depot-medroxyprogesterone acetate and bone mineral density in adolescent and young adult women with cerebral palsy

R. Claire Roden
, Garey Noritz
, Erin R. McKnight
, Andrea E. Bonny

Department of Pediatrics

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Objective: To explore whether use of depot-medroxyprogesterone acetate (DMPA) in adolescent and young adult females with cerebral palsy is associated with lower bone mineral density (BMD). Methods: A chart review of adolescent and young adult females with cerebral palsy who had undergone dual-energy X-ray absorptiometry, comparing BMD among those with (n = 19) and without DMPA (n = 84) exposure. Results: BMD was similar in patients with and without DMPA exposure. All patients had low BMD, with average Z-scores of less than −2 at most sites. Conclusion: Results suggest that DMPA is not associated with lower BMD in non-ambulatory adolescent and young adult females with cerebral palsy.

Original language	English (US)
Pages (from-to)	273-275
Number of pages	3
Journal	Contraception
Volume	101
Issue number	4
DOIs	https://doi.org/10.1016/j.contraception.2019.12.009
State	Published - Apr 2020

All Science Journal Classification (ASJC) codes

Reproductive Medicine
Obstetrics and Gynecology

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10.1016/j.contraception.2019.12.009

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title = "An exploratory study of depot-medroxyprogesterone acetate and bone mineral density in adolescent and young adult women with cerebral palsy",

abstract = "Objective: To explore whether use of depot-medroxyprogesterone acetate (DMPA) in adolescent and young adult females with cerebral palsy is associated with lower bone mineral density (BMD). Methods: A chart review of adolescent and young adult females with cerebral palsy who had undergone dual-energy X-ray absorptiometry, comparing BMD among those with (n = 19) and without DMPA (n = 84) exposure. Results: BMD was similar in patients with and without DMPA exposure. All patients had low BMD, with average Z-scores of less than −2 at most sites. Conclusion: Results suggest that DMPA is not associated with lower BMD in non-ambulatory adolescent and young adult females with cerebral palsy.",

author = "Roden, \{R. Claire\} and Garey Noritz and McKnight, \{Erin R.\} and Bonny, \{Andrea E.\}",

note = "Funding Information: Funding Support: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Financial Disclosure: The authors have no financial relationships relevant to this article to disclose. Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2020",

month = apr,

doi = "10.1016/j.contraception.2019.12.009",

language = "English (US)",

volume = "101",

pages = "273--275",

journal = "Contraception",

issn = "0010-7824",

publisher = "Elsevier Inc.",

number = "4",

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TY - JOUR

T1 - An exploratory study of depot-medroxyprogesterone acetate and bone mineral density in adolescent and young adult women with cerebral palsy

AU - Roden, R. Claire

AU - Noritz, Garey

AU - McKnight, Erin R.

AU - Bonny, Andrea E.

N1 - Funding Information: Funding Support: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Financial Disclosure: The authors have no financial relationships relevant to this article to disclose. Publisher Copyright: © 2019 Elsevier Inc.

PY - 2020/4

Y1 - 2020/4

N2 - Objective: To explore whether use of depot-medroxyprogesterone acetate (DMPA) in adolescent and young adult females with cerebral palsy is associated with lower bone mineral density (BMD). Methods: A chart review of adolescent and young adult females with cerebral palsy who had undergone dual-energy X-ray absorptiometry, comparing BMD among those with (n = 19) and without DMPA (n = 84) exposure. Results: BMD was similar in patients with and without DMPA exposure. All patients had low BMD, with average Z-scores of less than −2 at most sites. Conclusion: Results suggest that DMPA is not associated with lower BMD in non-ambulatory adolescent and young adult females with cerebral palsy.

AB - Objective: To explore whether use of depot-medroxyprogesterone acetate (DMPA) in adolescent and young adult females with cerebral palsy is associated with lower bone mineral density (BMD). Methods: A chart review of adolescent and young adult females with cerebral palsy who had undergone dual-energy X-ray absorptiometry, comparing BMD among those with (n = 19) and without DMPA (n = 84) exposure. Results: BMD was similar in patients with and without DMPA exposure. All patients had low BMD, with average Z-scores of less than −2 at most sites. Conclusion: Results suggest that DMPA is not associated with lower BMD in non-ambulatory adolescent and young adult females with cerebral palsy.

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DO - 10.1016/j.contraception.2019.12.009

M3 - Article

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ER -

An exploratory study of depot-medroxyprogesterone acetate and bone mineral density in adolescent and young adult women with cerebral palsy

Abstract

All Science Journal Classification (ASJC) codes

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