TY - GEN
T1 - An improved real-time cine Late Gadolinium Enhancement (LGE) imaging method at 3T
AU - Kadbi, Mo
AU - Kotys, Melanie
AU - Alshaher, Motaz
AU - Fischer, Stefan
AU - Amini, Amir A.
PY - 2011
Y1 - 2011
N2 - A real-time Late Gadolinium Enhancement (LGE) MRI technique (free breathing and non-gated) is presented for detection of myocardial scars. Conventional LGE imaging methods currently in use are applied in conjunction with breath-hold and, thus, are difficult to use in patients with cardiac disease and may lead to motion artifacts. Additionally, conventional techniques involve ECG gating, which is problematic in patients with arrhythmias requiring multiple breath holds and use of arrhythmia rejection techniques. Finally, conventional LGE techniques require accurate estimates for the inversion time in order to null the normal myocardium, revealing the location of the scar with high contrast. Real-time LGE imaging obviates these difficulties and can, in principle, acquire cine images to assess wall motion over several heart phases as part of the same scan. To date, the main limitation of real-time LGE imaging has been long acquisition window and low temporal resolution. These limitations lead to temporal blurring of wall motion and possible overestimation of infarct size. The goal of this study was to increase the temporal resolution of real-time, cine LGE imaging, providing the possibility for better visualization of the wall motion and more accurate assessment of myocardial viability.
AB - A real-time Late Gadolinium Enhancement (LGE) MRI technique (free breathing and non-gated) is presented for detection of myocardial scars. Conventional LGE imaging methods currently in use are applied in conjunction with breath-hold and, thus, are difficult to use in patients with cardiac disease and may lead to motion artifacts. Additionally, conventional techniques involve ECG gating, which is problematic in patients with arrhythmias requiring multiple breath holds and use of arrhythmia rejection techniques. Finally, conventional LGE techniques require accurate estimates for the inversion time in order to null the normal myocardium, revealing the location of the scar with high contrast. Real-time LGE imaging obviates these difficulties and can, in principle, acquire cine images to assess wall motion over several heart phases as part of the same scan. To date, the main limitation of real-time LGE imaging has been long acquisition window and low temporal resolution. These limitations lead to temporal blurring of wall motion and possible overestimation of infarct size. The goal of this study was to increase the temporal resolution of real-time, cine LGE imaging, providing the possibility for better visualization of the wall motion and more accurate assessment of myocardial viability.
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U2 - 10.1109/IEMBS.2011.6090097
DO - 10.1109/IEMBS.2011.6090097
M3 - Conference contribution
C2 - 22254365
AN - SCOPUS:84861944091
SN - 9781424441211
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 531
EP - 534
BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Y2 - 30 August 2011 through 3 September 2011
ER -