An On-chip, multichannel droplet sorter using standing surface acoustic waves

  • Sixing Li
  • , Xiaoyun Ding
  • , Feng Guo
  • , Yuchao Chen
  • , Michael Ian Lapsley
  • , Sz Chin Steven Lin
  • , Lin Wang
  • , J. Philip McCoy
  • , Craig E. Cameron
  • , Tony Jun Huang

Research output: Contribution to journalArticlepeer-review

Abstract

The emerging field of droplet microfluidics requires effective on-chip handling and sorting of droplets. In this work, we demonstrate a microfluidic device that is capable of sorting picoliter water-in-oil droplets into multiple outputs using standing surface acoustic waves (SSAW). This device integrates a single-layer microfluidic channel with interdigital transducers (IDTs) to achieve on-chip droplet generation and sorting. Within the SSAW field, water-in-oil droplets experience an acoustic radiation force and are pushed toward the acoustic pressure node. As a result, by tuning the frequency of the SSAW excitation, the position of the pressure nodes can be changed and droplets can be sorted to different outlets at rates up to 222 droplets s-1. With its advantages in simplicity, controllability, versatility, noninvasiveness, and capability to be integrated with other on-chip components such as droplet manipulation and optical detection units, the technique presented here could be valuable for the development of droplet-based micro total analysis systems (μTAS).

Original languageEnglish (US)
Pages (from-to)5468-5474
Number of pages7
JournalAnalytical Chemistry
Volume85
Issue number11
DOIs
StatePublished - Jun 4 2013

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

Fingerprint

Dive into the research topics of 'An On-chip, multichannel droplet sorter using standing surface acoustic waves'. Together they form a unique fingerprint.

Cite this