Analysis and modification of opiate reinforcement

Roger E. Meyer, H. Brian Mcnamee, Steven M. Mirin, Jack L. Altman

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The authors describe a research protocol for the evaluation of narcotic antagonists which examines the heroin-seeking behavior of hard-core heroin addicts on a research ward under blocked and unblocked conditions. Each patient served as his own control. This paper serves as an introduction to a series of papers which follow dealing with behavioral, psychiatric, and aftercare results. It describes detailed methods and preliminary results for the first 21 subjects admitted to the study. More specific results are reported in the papers that follow.

Original languageEnglish (US)
Pages (from-to)467-484
Number of pages18
JournalSubstance Use and Misuse
Issue number3
StatePublished - 1976

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health


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