TY - JOUR
T1 - Ancestral polyploidy in seed plants and angiosperms
AU - Jiao, Yuannian
AU - Wickett, Norman J.
AU - Ayyampalayam, Saravanaraj
AU - Chanderbali, André S.
AU - Landherr, Lena
AU - Ralph, Paula E.
AU - Tomsho, Lynn P.
AU - Hu, Yi
AU - Liang, Haiying
AU - Soltis, Pamela S.
AU - Soltis, Douglas E.
AU - Clifton, Sandra W.
AU - Schlarbaum, Scott E.
AU - Schuster, Stephan C.
AU - Ma, Hong
AU - Leebens-Mack, Jim
AU - Depamphilis, Claude W.
N1 - Funding Information:
Acknowledgements This work was supported primarily by NSF Plant Genome Research Program (DEB 0638595, The Ancestral Angiosperm Genome Project) and in part by the Department of Biology and by the Huck Institutes of Life Sciences of the Pennsylvania State University. H.M. was also supported by funds from Fudan University. We thank J. Carlson, M. Frohlich, S. DiLoretto, L. Warg, S. Crutchfield, C. Johnson, N. Naznin, X. Zhou, J. Duarte, B. J. Bliss, J. Der and E. Wafula for help and discussion, D. Stevenson and C. Schultz for Zamia samples, J. McNeal, S. Kim and M. Axtell for photographs, and all the members of The Genome Center at Washington University production team, especially L. Fulton, K. Delehaunty and C. Fronick.
PY - 2011/5/5
Y1 - 2011/5/5
N2 - Whole-genome duplication (WGD), or polyploidy, followed by gene loss and diploidization has long been recognized as an important evolutionary force in animals, fungi and other organisms, especially plants. The success of angiosperms has been attributed, in part, to innovations associated with gene or whole-genome duplications, but evidence for proposed ancient genome duplications pre-dating the divergence of monocots and eudicots remains equivocal in analyses of conserved gene order. Here we use comprehensive phylogenomic analyses of sequenced plant genomes and more than 12.6 million new expressed-sequence-tag sequences from phylogenetically pivotal lineages to elucidate two groups of ancient gene duplications-one in the common ancestor of extant seed plants and the other in the common ancestor of extant angiosperms. Gene duplication events were intensely concentrated around 319 and 192 million years ago, implicating two WGDs in ancestral lineages shortly before the diversification of extant seed plants and extant angiosperms, respectively. Significantly, these ancestral WGDs resulted in the diversification of regulatory genes important to seed and flower development, suggesting that they were involved in major innovations that ultimately contributed to the rise and eventual dominance of seed plants and angiosperms.
AB - Whole-genome duplication (WGD), or polyploidy, followed by gene loss and diploidization has long been recognized as an important evolutionary force in animals, fungi and other organisms, especially plants. The success of angiosperms has been attributed, in part, to innovations associated with gene or whole-genome duplications, but evidence for proposed ancient genome duplications pre-dating the divergence of monocots and eudicots remains equivocal in analyses of conserved gene order. Here we use comprehensive phylogenomic analyses of sequenced plant genomes and more than 12.6 million new expressed-sequence-tag sequences from phylogenetically pivotal lineages to elucidate two groups of ancient gene duplications-one in the common ancestor of extant seed plants and the other in the common ancestor of extant angiosperms. Gene duplication events were intensely concentrated around 319 and 192 million years ago, implicating two WGDs in ancestral lineages shortly before the diversification of extant seed plants and extant angiosperms, respectively. Significantly, these ancestral WGDs resulted in the diversification of regulatory genes important to seed and flower development, suggesting that they were involved in major innovations that ultimately contributed to the rise and eventual dominance of seed plants and angiosperms.
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U2 - 10.1038/nature09916
DO - 10.1038/nature09916
M3 - Article
C2 - 21478875
AN - SCOPUS:79955630390
SN - 0028-0836
VL - 473
SP - 97
EP - 100
JO - Nature
JF - Nature
IS - 7345
ER -