ANCOVA methods for heteroscedastic nonparametric regression models

Michael G. Akritas, Ingrid Van Keilegom

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


We consider an ANCOVA design in which the relationship between the response Yi and the covariate Xi in cell (factor-level combination) i satisfies the model Yi = mi(Xi)+σi(Xii, where the error term ϵi is assumed to be independent of Xi, and mi and σi are respectively a smooth (but unknown) regression and scale function. This model can be viewed as a generalization of the nonparametric ANCOVA model of Young and Bowman. As such it is a useful alternative for parametric or semiparametric ANCOVA models, whenever modeling assumptions such as proportional odds, normality of the error terms, linearity or homoscedasticity appear suspect. We develop test statistics for the hypotheses of no main effects, no interaction effects, and no simple effects, which adjust for the covariate values, as defined by Akritas, Arnold, and Du. The asymptotic distribution of the test statistics is obtained, its small sample behavior is studied by means of simulations and a real dataset is analyzed.

Original languageEnglish (US)
Pages (from-to)220-232
Number of pages13
JournalJournal of the American Statistical Association
Issue number453
StatePublished - Mar 1 2001

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Statistics, Probability and Uncertainty


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