Ankle bracing practices in ambulatory, corticosteroid-naive boys with Duchenne muscular dystrophy

The Muscle Study Group and TREAT-NMD

Research output: Contribution to journalArticlepeer-review


Introduction: Loss of ambulation in Duchenne muscular dystrophy presages scoliosis, respiratory failure, and death. Strategies to maintain ankle range of motion are employed, but little evidence exists to support these approaches and limited information is available concerning current practice. Methods: In this study we assessed baseline bracing data from 187 boys participating in a multicenter, international clinical trial. Results: Ankle-foot orthoses (AFOs) were recommended for 54% of the boys, with nighttime static AFOs and nighttime dynamic AFOs utilized in 94% and 6% of these boys, respectively. Daytime static AFOs were recommended for 3 boys. Compliance with bracing recommendations was 54% for nighttime static braces and 67% for nighttime dynamic braces. Discussion: The basis for the variation in recommended AFO use is unknown and requires further study. Long-term follow-up of boys may permit assessment of the effects of AFO use.

Original languageEnglish (US)
Pages (from-to)52-57
Number of pages6
JournalMuscle and Nerve
Issue number1
StatePublished - Jan 1 2020

All Science Journal Classification (ASJC) codes

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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