TY - JOUR
T1 - Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology
AU - Mohammed, A. B.Abeer
AU - Mohamed, Amr
AU - El-Naggar, Noura El Ahmady
AU - Mahrous, Hoda
AU - Nasr, Ghada M.
AU - Abdella, Asmaa
AU - Ahmed, Rasha H.
AU - Irmak, Sibel
AU - Elsayed, Mohamed S.A.
AU - Selim, Samy
AU - Elkelish, Amr
AU - Alkhalifah, Dalal Hussien M.
AU - Hozzein, Wael N.
AU - Ali, Abdallah S.
N1 - Publisher Copyright:
© 2022 A. B. Abeer Mohammed et al.
PY - 2022
Y1 - 2022
N2 - The research highlights the environmentally sustainable biosynthesis of silver nanoparticles from fresh leaves of the herbal medicinal plant Moringa oleifera. They may have been used as anti-inflammatory, anticancer, and antimicrobial agents. M. oleifera extract both reduces and stabilizes silver nanoparticles (AgNPs). Optimum factors needed for AgNP biosynthesis were studied using a central composite design (CCD) matrix. Ultraviolet-visible (UV-Vis) absorption spectroscopy, transmission electron microscopy, and Fourier-transform infrared spectroscopy were used to confirm and characterize the synthesized AgNPs. The biogenic AgNPs demonstrated substantial antibacterial potential against the pathogenic strains Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus subtilis. The antioxidant activity of biosynthesized AgNPs with M. oleifera extract increased from 11.96% when the concentration of the extract was 4 mg/mL to 63.79% at a plant concentration of 20 mg/mL. This research provides an easy and cost-effective technique for the production of stable nanoparticles, with an evaluation of their bioactivity.
AB - The research highlights the environmentally sustainable biosynthesis of silver nanoparticles from fresh leaves of the herbal medicinal plant Moringa oleifera. They may have been used as anti-inflammatory, anticancer, and antimicrobial agents. M. oleifera extract both reduces and stabilizes silver nanoparticles (AgNPs). Optimum factors needed for AgNP biosynthesis were studied using a central composite design (CCD) matrix. Ultraviolet-visible (UV-Vis) absorption spectroscopy, transmission electron microscopy, and Fourier-transform infrared spectroscopy were used to confirm and characterize the synthesized AgNPs. The biogenic AgNPs demonstrated substantial antibacterial potential against the pathogenic strains Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus subtilis. The antioxidant activity of biosynthesized AgNPs with M. oleifera extract increased from 11.96% when the concentration of the extract was 4 mg/mL to 63.79% at a plant concentration of 20 mg/mL. This research provides an easy and cost-effective technique for the production of stable nanoparticles, with an evaluation of their bioactivity.
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U2 - 10.1155/2022/9984308
DO - 10.1155/2022/9984308
M3 - Article
AN - SCOPUS:85129502561
SN - 1687-4110
VL - 2022
JO - Journal of Nanomaterials
JF - Journal of Nanomaterials
M1 - 9984308
ER -