Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology

A. B.Abeer Mohammed, Amr Mohamed, Noura El Ahmady El-Naggar, Hoda Mahrous, Ghada M. Nasr, Asmaa Abdella, Rasha H. Ahmed, Sibel Irmak, Mohamed S.A. Elsayed, Samy Selim, Amr Elkelish, Dalal Hussien M. Alkhalifah, Wael N. Hozzein, Abdallah S. Ali

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

The research highlights the environmentally sustainable biosynthesis of silver nanoparticles from fresh leaves of the herbal medicinal plant Moringa oleifera. They may have been used as anti-inflammatory, anticancer, and antimicrobial agents. M. oleifera extract both reduces and stabilizes silver nanoparticles (AgNPs). Optimum factors needed for AgNP biosynthesis were studied using a central composite design (CCD) matrix. Ultraviolet-visible (UV-Vis) absorption spectroscopy, transmission electron microscopy, and Fourier-transform infrared spectroscopy were used to confirm and characterize the synthesized AgNPs. The biogenic AgNPs demonstrated substantial antibacterial potential against the pathogenic strains Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus subtilis. The antioxidant activity of biosynthesized AgNPs with M. oleifera extract increased from 11.96% when the concentration of the extract was 4 mg/mL to 63.79% at a plant concentration of 20 mg/mL. This research provides an easy and cost-effective technique for the production of stable nanoparticles, with an evaluation of their bioactivity.

Original languageEnglish (US)
Article number9984308
JournalJournal of Nanomaterials
Volume2022
DOIs
StatePublished - 2022

All Science Journal Classification (ASJC) codes

  • General Materials Science

Fingerprint

Dive into the research topics of 'Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology'. Together they form a unique fingerprint.

Cite this