Apparatus for controlled microwave exposure of aerosolized pathogens

Brad W. Hoff; Jeremy W. McConaha; Zane W. Cohick; Matthew A. Franzi; Daniel A. Enderich; David Revelli; Jason Cox; Hammad Irshad; Hugh H. Pohle; Andreas Schmitt-Sody; Samuel C. Schaub; Anthony E. Baros; Naomi C. Lewis; John W. Luginsland; Michael T. Lanagan; Steven Perini

doi:10.1063/5.0032823

Apparatus for controlled microwave exposure of aerosolized pathogens

Brad W. Hoff, Jeremy W. McConaha, Zane W. Cohick, Matthew A. Franzi, Daniel A. Enderich, David Revelli, Jason Cox, Hammad Irshad, Hugh H. Pohle, Andreas Schmitt-Sody, Samuel C. Schaub, Anthony E. Baros, Naomi C. Lewis, John W. Luginsland, Michael T. Lanagan, Steven Perini

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9 Scopus citations

Abstract

A set of three apparatus enabling RF exposure of aerosolized pathogens at four chosen frequencies (2.8 GHz, 4.0 GHz, 5.6 GHz, and 7.5 GHz) has been designed, simulated, fabricated, and tested. Each apparatus was intended to operate at high power without leakage of RF into the local environment and to be compact enough to fit within biocontainment enclosures required for elevated biosafety levels. Predictions for the range of RF electric field exposure, represented by the complex electric field vector magnitude, that an aerosol stream would be expected to encounter while passing through the apparatus are calculated for each of the chosen operating frequencies.

Original language	English (US)
Article number	014707
Journal	Review of Scientific Instruments
Volume	92
Issue number	1
DOIs	https://doi.org/10.1063/5.0032823
State	Published - Jan 1 2021

All Science Journal Classification (ASJC) codes

Instrumentation

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10.1063/5.0032823

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Hoff, B. W., McConaha, J. W., Cohick, Z. W., Franzi, M. A., Enderich, D. A., Revelli, D., Cox, J., Irshad, H., Pohle, H. H., Schmitt-Sody, A., Schaub, S. C., Baros, A. E., Lewis, N. C., Luginsland, J. W., Lanagan, M. T., & Perini, S. (2021). Apparatus for controlled microwave exposure of aerosolized pathogens. Review of Scientific Instruments, 92(1), Article 014707. https://doi.org/10.1063/5.0032823

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title = "Apparatus for controlled microwave exposure of aerosolized pathogens",

abstract = "A set of three apparatus enabling RF exposure of aerosolized pathogens at four chosen frequencies (2.8 GHz, 4.0 GHz, 5.6 GHz, and 7.5 GHz) has been designed, simulated, fabricated, and tested. Each apparatus was intended to operate at high power without leakage of RF into the local environment and to be compact enough to fit within biocontainment enclosures required for elevated biosafety levels. Predictions for the range of RF electric field exposure, represented by the complex electric field vector magnitude, that an aerosol stream would be expected to encounter while passing through the apparatus are calculated for each of the chosen operating frequencies.",

author = "Hoff, {Brad W.} and McConaha, {Jeremy W.} and Cohick, {Zane W.} and Franzi, {Matthew A.} and Enderich, {Daniel A.} and David Revelli and Jason Cox and Hammad Irshad and Pohle, {Hugh H.} and Andreas Schmitt-Sody and Schaub, {Samuel C.} and Baros, {Anthony E.} and Lewis, {Naomi C.} and Luginsland, {John W.} and Lanagan, {Michael T.} and Steven Perini",

note = "Funding Information: This work was funded by the Air Force Research Laboratory and the Air Force Office of Scientific Research portfolio for Aerospace Materials for Extreme Environments under AFOSR (Grant No. LRIR 20RDCOR022). The authors thank the VIDER Senior Leadership Panel (K. Hammett, K. Geiss, S. Welsh, D. Shif-fler, R. Naik, P. Roach, S. Miller, and M. Ewy) for providing guidance and the other VIDER team leads (B. Ibey, J. Payne, R. Thomas, and I. Echchgadda) for helpful technical discussions. The authors acknowledge additional helpful discussions with D. French, P. Mardahl, J. MagGillivray, B. Jawdat, B. R. Jayan, and P. Kuehl. Cleared for public release (Reference No. OPS-20-39011, Case No. AFRL-2020-0138). Publisher Copyright: {\textcopyright} 2021 U.S. Government.",

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AU - Hoff, Brad W.

AU - McConaha, Jeremy W.

AU - Cohick, Zane W.

AU - Franzi, Matthew A.

AU - Enderich, Daniel A.

AU - Revelli, David

AU - Cox, Jason

AU - Irshad, Hammad

AU - Pohle, Hugh H.

AU - Schmitt-Sody, Andreas

AU - Schaub, Samuel C.

AU - Baros, Anthony E.

AU - Lewis, Naomi C.

AU - Luginsland, John W.

AU - Lanagan, Michael T.

AU - Perini, Steven

N1 - Funding Information: This work was funded by the Air Force Research Laboratory and the Air Force Office of Scientific Research portfolio for Aerospace Materials for Extreme Environments under AFOSR (Grant No. LRIR 20RDCOR022). The authors thank the VIDER Senior Leadership Panel (K. Hammett, K. Geiss, S. Welsh, D. Shif-fler, R. Naik, P. Roach, S. Miller, and M. Ewy) for providing guidance and the other VIDER team leads (B. Ibey, J. Payne, R. Thomas, and I. Echchgadda) for helpful technical discussions. The authors acknowledge additional helpful discussions with D. French, P. Mardahl, J. MagGillivray, B. Jawdat, B. R. Jayan, and P. Kuehl. Cleared for public release (Reference No. OPS-20-39011, Case No. AFRL-2020-0138). Publisher Copyright: © 2021 U.S. Government.

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AB - A set of three apparatus enabling RF exposure of aerosolized pathogens at four chosen frequencies (2.8 GHz, 4.0 GHz, 5.6 GHz, and 7.5 GHz) has been designed, simulated, fabricated, and tested. Each apparatus was intended to operate at high power without leakage of RF into the local environment and to be compact enough to fit within biocontainment enclosures required for elevated biosafety levels. Predictions for the range of RF electric field exposure, represented by the complex electric field vector magnitude, that an aerosol stream would be expected to encounter while passing through the apparatus are calculated for each of the chosen operating frequencies.

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Apparatus for controlled microwave exposure of aerosolized pathogens

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