TY - JOUR
T1 - Application areas of 3D bioprinting
AU - Ozbolat, Ibrahim T.
AU - Peng, Weijie
AU - Ozbolat, Veli
N1 - Funding Information:
Weijie Peng received his PhD degree from the Department of Pharmacology, Central South University, China, in 2005. He is an Associate Professor in the Department of Pharmacology, Nanchang University, China. He has recently joined the Ozbolat Lab at Penn State University as a visiting scholar supported by the Chinese Scholarship Committee. His major research work is on estrogen receptor, estrogenic substances and bioprinting for pharmaceutical research.
Funding Information:
This work has been supported by National Science Foundation CMMI Awards 1349716 and 1462232 , Diabetes in Action Research and Education Foundation grant #426 and the China Scholarship Council 201308360128 .
Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Three dimensional (3D) bioprinting has been a powerful tool in patterning and precisely placing biologics, including living cells, nucleic acids, drug particles, proteins and growth factors, to recapitulate tissue anatomy, biology and physiology. Since the first time of cytoscribing cells demonstrated in 1986, bioprinting has made a substantial leap forward, particularly in the past 10 years, and it has been widely used in fabrication of living tissues for various application areas. The technology has been recently commercialized by several emerging businesses, and bioprinters and bioprinted tissues have gained significant interest in medicine and pharmaceutics. This Keynote review presents the bioprinting technology and covers a first-time comprehensive overview of its application areas from tissue engineering and regenerative medicine to pharmaceutics and cancer research.
AB - Three dimensional (3D) bioprinting has been a powerful tool in patterning and precisely placing biologics, including living cells, nucleic acids, drug particles, proteins and growth factors, to recapitulate tissue anatomy, biology and physiology. Since the first time of cytoscribing cells demonstrated in 1986, bioprinting has made a substantial leap forward, particularly in the past 10 years, and it has been widely used in fabrication of living tissues for various application areas. The technology has been recently commercialized by several emerging businesses, and bioprinters and bioprinted tissues have gained significant interest in medicine and pharmaceutics. This Keynote review presents the bioprinting technology and covers a first-time comprehensive overview of its application areas from tissue engineering and regenerative medicine to pharmaceutics and cancer research.
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U2 - 10.1016/j.drudis.2016.04.006
DO - 10.1016/j.drudis.2016.04.006
M3 - Review article
C2 - 27086009
AN - SCOPUS:84964692969
SN - 1359-6446
VL - 21
SP - 1257
EP - 1271
JO - Drug Discovery Today
JF - Drug Discovery Today
IS - 8
ER -
