Application of atomic force microscope to the study of bio-cells

Bernhard Tittmann; Jikai Du; Anne Ebert; Brian Piccione

doi:10.1117/12.598871

Application of atomic force microscope to the study of bio-cells

Bernhard Tittmann, Jikai Du, Anne Ebert, Brian Piccione

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used in this work assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both nonviable and viable materials. Improvement of our system for living cell (in a culture) imaging is also discussed.

Original language	English (US)
Article number	02
Pages (from-to)	11-18
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5768
DOIs	https://doi.org/10.1117/12.598871
State	Published - 2005
Event	Health Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems IV - San Diego, CA, United States Duration: Mar 7 2005 → Mar 9 2005

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.598871

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title = "Application of atomic force microscope to the study of bio-cells",

abstract = "Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used in this work assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both nonviable and viable materials. Improvement of our system for living cell (in a culture) imaging is also discussed.",

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T1 - Application of atomic force microscope to the study of bio-cells

AU - Tittmann, Bernhard

AU - Du, Jikai

AU - Ebert, Anne

AU - Piccione, Brian

PY - 2005

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N2 - Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used in this work assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both nonviable and viable materials. Improvement of our system for living cell (in a culture) imaging is also discussed.

AB - Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used in this work assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both nonviable and viable materials. Improvement of our system for living cell (in a culture) imaging is also discussed.

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ER -

Application of atomic force microscope to the study of bio-cells

Abstract

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