Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients

Brendan McClafferty, Ibrahim Umer, Gary Fye, Douglas Kepko, Ricci Kalayanamitra, Zainab Shahid, Devyani Ramgobin, Alice Cai, Andrew Groff, Abani Bhandari, Chander Shekher Aggarwal, Ravi Patel, Dhirisha Bhatt, Hyma Polimera, Nitasa Sahu, Ramarao Vunnam, Reshma Golamari, Ashutosh Kumar, Rohit Jain

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


One of the major concerns of the health care community and the public surrounding the SARS-CoV-2 pandemic is the availability and use of ventilators. Unprecedented surges of patients presented to intensive care units across the country, with older adults making up a large proportion of the patient population. This paper illustrates contemporary approaches to critical illness myopathy (CIM), critical illness polyneuropathy (CIP), and critical illness polyneuromyopathy (CIPNM) in older patients, including incidence, risk factors, mechanisms for pathology, diagnosis, contemporary treatment approaches, and outcomes. We hope that the following analysis may help educate clinicians and ultimately decrease the duration of the mechanical ventilation required by these patients, resulting in improved clinical outcomes and an increase in ventilator availability for other patients in need.

Original languageEnglish (US)
Pages (from-to)241-245
Number of pages5
JournalJournal of Clinical Neuroscience
StatePublished - Sep 2020

All Science Journal Classification (ASJC) codes

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)


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