Approaching the mechanism of protein transport across the ER membrane

Tom A. Rapoport, Melissa M. Rolls, Berit Jungnickel

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


Since the identification of essential protein-translocation components in the endoplasmic reticulum membrane, research efforts have concentrated on the elucidation of the molecular mechanism of protein transport across this membrane. Recent results have provided new information as to how proteins are targeted to, and inserted into, the translocation site during translation. Post-translational translocation has also been examined and is distinct from cotranslational translocation with respect to the mechanism and membrane protein components involved.

Original languageEnglish (US)
Pages (from-to)499-504
Number of pages6
JournalCurrent Opinion in Cell Biology
Issue number4
StatePublished - Aug 1996

All Science Journal Classification (ASJC) codes

  • Cell Biology


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