Aqueous computing: A survey with an invitation to participate

Tom Head, Xia Chen, Masayuki Yamamura, Susannah Gal

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The concept of aqueous computing is presented here, first in full generality, and afterward, using an implementation in a specific enzymatic technology. Aqueous computing arose in the context of biomolecular (DNA) computing, but the concept is independent of the specifics of its biochemical origin. Alternate technologies for realizing aqueous computing are being considered for future implementation. A solution of an instance of the Boolean satisfiability problem, (SAT), is reported here that provides a new example of an aqueous computation that has been carried out successfully. This small instance of the SAT problem is sufficiently complex to allow our current enzymatic technology to be illustrated in detail. The reader is invited to participate in the rich interdisciplinary activity required by wet lab computing. A project is suggested to the reader for determining the three-colorings of a graph. The basic operations required for this project are exhibited in the solution of the SAT example reported here.

Original languageEnglish (US)
Pages (from-to)672-681
Number of pages10
JournalJournal of Computer Science and Technology
Issue number6
StatePublished - Nov 2002

All Science Journal Classification (ASJC) codes

  • Software
  • Theoretical Computer Science
  • Hardware and Architecture
  • Computer Science Applications
  • Computational Theory and Mathematics


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