Arachidonic acid metabolism by the non-pregnant human uterus

Laurence M. Demers; Margaret C.P. Rees; A. C. Turnbull

doi:10.1016/0262-1746(84)90199-9

Arachidonic acid metabolism by the non-pregnant human uterus

Laurence M. Demers, Margaret C.P. Rees, A. C. Turnbull

Department of Pathology and Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Arachidonic acid metabolism in the non-pregnant human uterus was studied using short term incubations of human endometrium and myometrium with [¹⁴C] arachidonic acid followed by HPLC separation of the arachi donic acid metabolites formed. Lipoxygenase as well as cyclooxygenase activity was found in both the endometrium and myometrium although the endometrium predominated in arachidonic acid product formation. The lipoxygenase products formed by these tissues included the monohydroxy acids 5 5-HETE and 12-HETE.

Original language	English (US)
Pages (from-to)	175-180
Number of pages	6
Journal	Prostaglandins, Leukotrienes and Medicine
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/0262-1746(84)90199-9
State	Published - May 1984

All Science Journal Classification (ASJC) codes

Biochemistry
Physiology
Endocrinology

Access to Document

10.1016/0262-1746(84)90199-9

Cite this

@article{7f211393d45f4fe087987a0b7101105f,

title = "Arachidonic acid metabolism by the non-pregnant human uterus",

abstract = "Arachidonic acid metabolism in the non-pregnant human uterus was studied using short term incubations of human endometrium and myometrium with [14C] arachidonic acid followed by HPLC separation of the arachi donic acid metabolites formed. Lipoxygenase as well as cyclooxygenase activity was found in both the endometrium and myometrium although the endometrium predominated in arachidonic acid product formation. The lipoxygenase products formed by these tissues included the monohydroxy acids 5 5-HETE and 12-HETE.",

author = "Demers, {Laurence M.} and Rees, {Margaret C.P.} and Turnbull, {A. C.}",

year = "1984",

month = may,

doi = "10.1016/0262-1746(84)90199-9",

language = "English (US)",

volume = "14",

pages = "175--180",

journal = "Prostaglandins, Leukotrienes and Medicine",

issn = "0262-1746",

publisher = "Churchill Livingstone",

number = "2",

}

TY - JOUR

T1 - Arachidonic acid metabolism by the non-pregnant human uterus

AU - Demers, Laurence M.

AU - Rees, Margaret C.P.

AU - Turnbull, A. C.

PY - 1984/5

Y1 - 1984/5

N2 - Arachidonic acid metabolism in the non-pregnant human uterus was studied using short term incubations of human endometrium and myometrium with [14C] arachidonic acid followed by HPLC separation of the arachi donic acid metabolites formed. Lipoxygenase as well as cyclooxygenase activity was found in both the endometrium and myometrium although the endometrium predominated in arachidonic acid product formation. The lipoxygenase products formed by these tissues included the monohydroxy acids 5 5-HETE and 12-HETE.

AB - Arachidonic acid metabolism in the non-pregnant human uterus was studied using short term incubations of human endometrium and myometrium with [14C] arachidonic acid followed by HPLC separation of the arachi donic acid metabolites formed. Lipoxygenase as well as cyclooxygenase activity was found in both the endometrium and myometrium although the endometrium predominated in arachidonic acid product formation. The lipoxygenase products formed by these tissues included the monohydroxy acids 5 5-HETE and 12-HETE.

UR - http://www.scopus.com/inward/record.url?scp=0021246626&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021246626&partnerID=8YFLogxK

U2 - 10.1016/0262-1746(84)90199-9

DO - 10.1016/0262-1746(84)90199-9

M3 - Article

C2 - 6429668

AN - SCOPUS:0021246626

SN - 0262-1746

VL - 14

SP - 175

EP - 180

JO - Prostaglandins, Leukotrienes and Medicine

JF - Prostaglandins, Leukotrienes and Medicine

IS - 2

ER -

Arachidonic acid metabolism by the non-pregnant human uterus

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this